Aquaporin-4 (AQP4) Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A2887-20, A2887-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. Additional isoforms, resulting from the use of alternative in-frame translation initiation codons, have also been described. Recent studies provided evidence for translational readthrough in this gene, and expression of C-terminally extended isoforms via the use of an alternative in-frame translation termination codon.
Synonyms: MIWC; WCH4; hAQP4; Aquaporin-4 (AQP4)
GeneID: 361
Swiss-Prot: P55087
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 35kDa
Observed Molecular Weight: 35kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 256-323 of human Aquaporin-4 (AQP4) (NP_001641.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:100 - 1:500 | IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:200
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Neuroscience, Neurodegenerative Diseases Markers, Other Neurological disorders
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: SKOV3
Cellular Location: Membrane, Multi-pass Membrane Protein
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.