CCKBR Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A2941-20, A2941-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.
Synonyms: GASR; CCK-B; CCK2R; CCKBR
GeneID: 887
Swiss-Prot: P32239
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 48kDa
Observed Molecular Weight: 50kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-335 of human CCKBR (NP_795344.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled Receptors (GPCR), Endocrine Metabolism, Endocrine and metabolic diseases, Obesity, Neuroscience
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Human stomach cancer tissue
Cellular Location: Cell Membrane, Multi-pass Membrane Protein
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.