CLDN4 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A2947-20, A2947-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
Synonyms: CPER; CPE-R; CPETR; CPETR1; WBSCR8; hCPE-R; CLDN4
GeneID: 1364
Swiss-Prot: O14493
Reactivity: Human
Calculated Molecular Weight: 22kDa
Observed Molecular Weight: 22kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human CLDN4 (NP_001296.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Tight Junctions, Cytoskeleton
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HT-29
Cellular Location: Cell Junction, Cell Membrane, Multi-pass Membrane Protein, tight Junction
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.