CX3CR1 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A2890-20, A2890-100
Citations, Manuals and SDS Available upon request.
Background: Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
Synonyms: V28; CCRL1; GPR13; CMKDR1; GPRV28; CMKBRL1; CX3CR1
GeneID: 1524
Swiss-Prot: P49238
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 40kDa
Observed Molecular Weight: 52kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CX3CR1 (NP_001328.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:100 - 1:500 | IHC-P: 1:50 - 1:200
Research Areas: Cancer, Invasion and Metastasis, Signal Transduction, G protein signaling, G-Protein-Coupled Receptors (GPCR), Cell Biology Developmental Biology, Cell Adhesion, Immunology Inflammation, Cell Intrinsic Innate Immunity Signaling Pathway, Neuroscience
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Raji, SH-SY5Y, Mouse spinal cord, Mouse brain, Rat testis
Cellular Location: Cell Membrane, Multi-pass Membrane Protein
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.