CXCR3 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A2939-20, A2939-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).
Synonyms: GPR9; MigR; CD182; CD183; Mig-R; CKR-L2; CMKAR3; IP10-R; CXCR3
GeneID: 2833
Swiss-Prot: P49682
Reactivity: Human, Mouse
Calculated Molecular Weight: 41kDa
Observed Molecular Weight: 44kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 289-368 of human CXCR3 (NP_001495.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:100
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled Receptors (GPCR), Immunology Inflammation, CDs, Cell Intrinsic Innate Immunity Signaling Pathway, Neuroscience, Calcium Signaling, Cardiovascular
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: 293T, K-562, HepG2, SGC996, SW620
Cellular Location: Cell Membrane, Multi-pass Membrane Protein
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.