DISC1 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A2898-20, A2898-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Synonyms: SCZD9; C1orf136; DISC1
GeneID: 27185
Swiss-Prot: Q9NRI5
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 94kDa
Observed Molecular Weight: 105kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human DISC1 (NP_001158009.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Epigenetics Nuclear Signaling, Cell Biology Developmental Biology, Cell Cycle, Centrosome, Neuroscience, Neurodegenerative Diseases, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: U-251MG, 293T, SW620, THP-1, mouse pancreas, mouse heart, rat brain, HL-60, Rat heart
Cellular Location: Cell Junction, Cytoplasm, Centrosome, Cytoskeleton, Microtubule Organizing Center, Postsynaptic Cell Membrane, Postsynaptic Density, Synapse
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.