DNM1 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A2902-20, A2902-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.
Synonyms: DNM; DEE31; EIEE31; DNM1
GeneID: 1759
Swiss-Prot: Q05193
Reactivity: Mouse, Rat
Calculated Molecular Weight: 97kDa
Observed Molecular Weight: 110kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 400-490 of human DNM1 (NP_004399.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled Receptors Signaling to MAPK Erk, Cell Biology Developmental Biology, Cell Adhesion, Immunology Inflammation, Neuroscience, Cell Type Marker, Neuron marker, Synapse marker
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Mouse brain, Rat brain
Cellular Location: Cytoplasm, Cytoskeleton
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.