DUSP1/MKP1 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A2919-20, A2919-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy.
Synonyms: HVH1; MKP1; CL100; MKP-1; PTPN10; DUSP1/MKP1
GeneID: 1843
Swiss-Prot: P28562
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 39kDa
Observed Molecular Weight: 40kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human DUSP1/MKP1 (NP_004408.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:100 - 1:500
Research Areas: Signal Transduction, Kinase, MAPK-Erk Signaling Pathway, MAPK-JNK Signaling Pathway
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Rat brain
Cellular Location: Nucleus
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.