EDA Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A2905-20, A2905-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.
Synonyms: ED1; HED; EDA1; EDA2; HED1; ODT1; XHED; ECTD1; XLHED; ED1-A1; ED1-A2; EDA-A1; EDA-A2; TNLG7C; STHAGX1; EDA
GeneID: 1896
Swiss-Prot: Q92838
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 41kDa
Observed Molecular Weight: 41kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 62-182 of human EDA (NP_001390.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:100 - 1:500 | IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:200
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Growth factors, Immunology Inflammation, Cytokines, Stem Cells
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HepG2
Cellular Location: Cell Membrane, Secreted, Single-pass Type II Membrane Protein
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.