EDNRB Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A2908-20, A2908-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Synonyms: ETB; ET-B; ETB1; ETBR; ETRB; HSCR; WS4A; ABCDS; ET-BR; HSCR2; EDNRB
GeneID: 1910
Swiss-Prot: P24530
Reactivity: Human, Mouse
Calculated Molecular Weight: 50kDa
Observed Molecular Weight: 49kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human EDNRB (NP_001116131.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled Receptors (GPCR)
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: B cells, Mouse lung, Mouse brain
Cellular Location: Cell Membrane, Multi-pass Membrane Protein
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.