EFNB3 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A2916-20, A2916-100
Citations, Manuals and SDS Available upon request.
Background: EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
Synonyms: EFL6; EPLG8; LERK8; EFNB3
GeneID: 1949
Swiss-Prot: Q15768
Reactivity: Human
Calculated Molecular Weight: 36kDa
Observed Molecular Weight: 36kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 28-226 of human EFNB3 (NP_001397.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:1000 - 1:4000
Research Areas: Kinase, Neuroscience, Cell Type Marker, Cardiovascular, Angiogenesis, Neuron marker
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: SH-SY5Y, HT-1080, SW480, SKOV3
Cellular Location: Membrane, Single-pass Type I Membrane Protein
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.