GJB3 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A2949-20, A2949-100
Citations, Manuals and SDS Available upon request.
Background: This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin disorder. Alternative splicing results in multiple transcript variants encoding the same protein.
Synonyms: EKV; CX31; DFNA2; EKVP1; DFNA2B; GJB3
GeneID: 2707
Swiss-Prot: O75712
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 31kDa
Observed Molecular Weight: 31kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human GJB3 (NP_076872.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:2000 - 1:50000
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Cytoskeleton, Neuroscience
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Mouse testis, Mouse intestine
Cellular Location: Cell Junction, Cell Membrane, Multi-pass Membrane Protein, gap Junction
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.