PGE receptor EP1 (PTGER1) Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A2913-20, A2913-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin.
Synonyms: EP1; PGE receptor EP1 (PTGER1)
GeneID: 5731
Swiss-Prot: P34995
Reactivity: Mouse
Calculated Molecular Weight: 42kDa
Observed Molecular Weight: 42kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 350-450 of human PGE receptor EP1 (PTGER1) (P34995).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled Receptors (GPCR)
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Mouse kidney
Cellular Location: Cell Membrane, Multi-pass Membrane Protein
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.