SFRP1 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A2911-20, A2911-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.
Synonyms: FRP; FRP1; FrzA; FRP-1; SARP2; SFRP1
GeneID: 6422
Swiss-Prot: Q8N474
Reactivity: Human, Mouse
Calculated Molecular Weight: 35kDa
Observed Molecular Weight: 35kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-314 of human SFRP1 (NP_003003.3).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:100
Research Areas: Cell Biology Developmental Biology, Apoptosis, Ubiquitin, Wnt ��-Catenin Signaling Pathway, Neuroscience, Stem Cells
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: NCI-H460, 293T, SKOV3, Mouse kidney
Cellular Location: Secreted
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.