ApoER2/LRP8 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9747-20, A9747-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms: MCI1; LRP-8; APOER2; HSZ75190; ApoER2/LRP8
GeneID: 7804
Swiss-Prot: Q14114
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 106kDa
Observed Molecular Weight: 100-106kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 864-963 of human ApoER2/LRP8 (Q14114).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Lipid Metabolism, Endocrine and metabolic diseases, Obesity, Neuroscience, Neurodegenerative Diseases, Cardiovascular, Lipids
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: U-87MG, Mouse testis, Rat testis
Cellular Location: Cell Membrane, Secreted, Single-pass Type I Membrane Protein
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.