CCR9 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9698-20, A9698-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the beta chemokine receptor family. Chemokines and their receptors are key regulators of thymocyte migration and maturation in normal and inflammation conditions. This gene is differentially expressed in T lymphocytes of the small intestine and colon, and its interaction with chemokine 25 contributes to intestinal intra-epithelial lymphocyte homing to the small intestine. This suggests a role for this gene in directing immune responses to different segments of the gastrointestinal tract. This gene and its exclusive ligand, chemokine 25, are overexpressed in a variety of malignant tumors and are closely associated with tumor proliferation, apoptosis, invasion, migration and drug resistance. This gene maps to the chemokine receptor gene cluster. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: GPR28; CDw199; GPR-9-6; CC-CKR-9; CCR9
GeneID: 10803
Swiss-Prot: P51686
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 42kDa
Observed Molecular Weight: 42kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CCR9 (NP_112477.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled Receptors (GPCR), Immunology Inflammation, CDs, Cell Intrinsic Innate Immunity Signaling Pathway
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: A549, Jurkat, U-937, Mouse lung, Mouse spleen, Rat lung, Rat spleen
Cellular Location: Cell Membrane,
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.