Collagen VI/COL6A1 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9738-20, A9738-100
Citations, Manuals and SDS Available upon request.
Background: The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.
Synonyms: OPLL; BTHLM1; UCHMD1; Collagen VI/COL6A1
GeneID: 1291
Swiss-Prot: P12109
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 109kDa
Observed Molecular Weight: 140kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 37-235 of human Collagen VI/COL6A1 (P12109).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cytoskeleton, Extracellular Matrix
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Mouse lung, Rat heart
Cellular Location: Secreted, Extra Cellular Matrix, Extra Cellular Space
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.