GRIK2 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9722-20, A9722-100
Citations, Manuals and SDS Available upon request.
Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive cognitive disability.
Synonyms: EAA4; GLR6; MRT6; GLUK6; GLUR6; GluK2; NEDLAS; GRIK2
GeneID: 2898
Swiss-Prot: Q13002
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 103kDa
Observed Molecular Weight: 100kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human GRIK2 (Q13002).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled Receptors (GPCR), Cell Biology Developmental Biology, Apoptosis, Neuroscience
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Mouse brain, 293T
Cellular Location: Cell Junction, Cell Membrane, Multi-pass Membrane Protein, PostSynaptic Cell Membrane, Synapse,
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.