IQGAP1 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9765-20, A9765-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.
Synonyms: SAR1; p195; HUMORFA01; IQGAP1
GeneID: 8826
Swiss-Prot: P46940
Reactivity: Human, Mouse
Calculated Molecular Weight: 189kDa
Observed Molecular Weight: 195kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IQGAP1 (NP_003861.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200
Research Areas: Cancer, Signal Transduction, G protein signaling, Small G proteins, Cell Biology Developmental Biology, Cell Adhesion, Endocrine Metabolism
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: U-87MG, Mouse lung
Cellular Location: Cell Membrane,
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.