PRP19 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9660-20, A9660-100
Citations, Manuals and SDS Available upon request.
Background: Enables identical protein binding activity and ubiquitin-ubiquitin ligase activity. Involved in several processes, including DNA damage checkpoint signaling; cellular protein metabolic process; and mRNA splicing, via spliceosome. Acts upstream of or within protein polyubiquitination. Located in cytoplasm; nuclear speck; and site of double-strand break. Part of Prp19 complex and U2-type catalytic step 2 spliceosome. Colocalizes with DNA replication factor A complex.
Synonyms: PSO4; SNEV; PRP19; UBOX4; hPSO4; NMP200
GeneID: 27339
Swiss-Prot: Q9UMS4
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 55kDa
Observed Molecular Weight: 55kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 400-504 of human PRPF19(Q9UMS4).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling, DNA Damage Repair, Cell Biology Developmental Biology, Ubiquitin, Ubiquitin-Proteasome Signaling Pathway
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, SKOV3, Mouse thymus, Rat spleen
Cellular Location: Cytoplasm, Lipid droplet, Nucleus, Cytoskeleton, Nucleoplasm, Spindle
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.