UAP56/DDX39B Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9749-20, A9749-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. This gene belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between this gene and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2) gene.
Synonyms: BAT1; UAP56; D6S81E; UAP56/DDX39B
GeneID: 7919
Swiss-Prot: Q13838
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 49kDa
Observed Molecular Weight: 49kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 310-428 of human UAP56/DDX39B (Q13838).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, MCF7, Mouse brain, Mouse spleen, Mouse thymus, Rat lung
Cellular Location: Cytoplasm, Nucleus, Nucleus speckle
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.